Literature summary for 3.4.24.17 extracted from

Komosinska-Vassev, K.; Olczyk, P.; Winsz-Szczotka, K.; Kuznik-Trocha, K.; Klimek, K.; Olczyk, K.
Age- and gender-dependent changes in connective tissue remodeling: physiological differences in circulating MMP-3, MMP-10, TIMP-1 and TIMP-2 Level (2010), Gerontology, 57, 44-52.

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Inhibitors

Inhibitors	Comment	Organism	Structure
TIMP-1	upregulated with age	Homo sapiens
TIMP-2	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Homo sapiens	-	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
45000	-	x * 57000, pro-MMP-3, SDS-PAGE, x * 45000, mature MMP-3, SDS-PAGE	Homo sapiens
57000	-	x * 57000, pro-MMP-3, SDS-PAGE, x * 45000, mature MMP-3, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	quantitative detection of pro- and active forms of MMP-3 in blood from healthy subjects of both genders and different ages, overview. MMP-3 and TIMP-1 serum levels are age-dependently increased, the relationship between age and MMP-3 serum levels is stronger in men compared to women	Homo sapiens	-

Subunits

Subunits	Comment	Organism
?	x * 57000, pro-MMP-3, SDS-PAGE, x * 45000, mature MMP-3, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
MMP-3	-	Homo sapiens
stromelysin-1	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	MMP-3 expression is upregulated with age, overview	up

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Release 2023.1 (January 2023)