Any feedback?
Literature summary for 3.4.24.17 extracted from
- Blood-brain barrier disruption by stromelysin-1 facilitates neutrophil infiltration in neuroinflammation (2006), Neurobiol. Dis., 23, 87-96.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | Less disruption of blood-brain barrier after intracerebral lipopolysaccharide injection in enzyme knockout animals than in wild-type. Mutant animals show lower level of matrix metalloproteinase MMP-9 but similar levels of activation as wild-type | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | enzyme attacks the basal lamina and tight junction proteins, opening the blood-brain barrier and thereby facilitating neutrophil influx | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme attacks the basal lamina and tight junction proteins, opening the blood-brain barrier and thereby facilitating neutrophil influx | Mus musculus | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
