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Literature summary for 3.4.24.17 extracted from

  • Parker, M.H.; Lunney, E.A.; Ortwine, D.F.; Pavlovsky, A.G.; Humblet, C.; Brouillette, C.G.
    Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry (1999), Biochemistry, 38, 13592-13601.
    View publication on PubMed

Application

Application Comment Organism
medicine attractive target for pharmaceutical design, implicated in diseases such as arthritis and cancer Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
recombinant SCD expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
galardin Glycomed GM-6001, clinically advanced MMP inhibitor, effective in treatment of corneal ulcers Homo sapiens
PD166793
-
Homo sapiens
PD180557
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Purification (Commentary)

Purification (Comment) Organism
recombinant SCD Homo sapiens

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-3
-
Homo sapiens
stromelysin-1
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
Homo sapiens