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Literature summary for 3.4.24.16 extracted from

  • Rioli, V.; Kato, A.; Portaro, F.C.V.; Cury, G.K.; te Kaat, K.; Vincent, B.; Checler, F.; Camargo, A.C.M.; Glucksman, M.J.; Roberts, J.L.; Hirose, S.; Ferro, E.S.
    Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15 (1998), Biochem. Biophys. Res. Commun., 250, 5-11.
    View publication on PubMed
Search for more literature for 3.4.24.16

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of enzyme form EP24.16m and EP24.16c in Escherichia coli Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
dithiothreitol
-
 Sus scrofa
Pro-Ile
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane EP24.16c is the cytosolic/membrane-bound enzyme form Sus scrofa 16020
-
mitochondrion EP24.16m is the mitochondrial enzyme form Sus scrofa 5739
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg + H2O i.e. bradykinin, cleavage site: Phe5-Ser6 Sus scrofa Arg-Pro-Pro-Gly-Phe + Ser-Pro-Phe-Arg
-
 ?
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O i.e. angiotensin I, cleavage site: Pro7-Phe8 Sus scrofa Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O specific hydrolysis of the Pro10-Tyr11 bond Sus scrofa pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O i.e. dynorphin(1-8) Sus scrofa Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?
Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-(NH2) + H2O i.e. metorphinamide Sus scrofa Tyr-Gly-Gly-Phe-Met + Arg-Arg-Val-(NH2)
-
 ?

Synonyms

Synonyms Comment Organism
EP24.16c the cytosolic/membrane bound enzyme form Sus scrofa
EP24.16m the mitochondrial enzyme form Sus scrofa