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Literature summary for 3.4.24.1 extracted from

  • Kruzel, M.; Kress, L.F.
    Separation of Crotalus atrox (western diamondback rattlesnake) alpha-proteinase from serine proteinase and hemorrhagic factor activities (1985), Anal. Biochem., 151, 471-478.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Crotalus atrox

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activates Crotalus atrox
Mg2+ activates Crotalus atrox

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26000
-
? * 26000, SDS-PAGE Crotalus atrox
26740
-
amino acid analysis Crotalus atrox

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Proteins + H2O Crotalus atrox preferential cleavage: -Leu, -Ile, -Val, -Phe ?
-
?

Organism

Organism UniProt Comment Textmining
Crotalus atrox
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
no modification non-glycosylated Crotalus atrox

Purification (Commentary)

Purification (Comment) Organism
-
Crotalus atrox

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Crotalus atrox
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Crotalus atrox

Storage Stability

Storage Stability Organism
18°C, 18 months Crotalus atrox

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha1-Antichymotrypsin + H2O
-
Crotalus atrox ?
-
?
casein + H2O preferential cleavage: -Leu, -Ile, -Val, -Phe Crotalus atrox ?
-
?
Proteins + H2O preferential cleavage: -Leu, -Ile, -Val, -Phe Crotalus atrox ?
-
?

Subunits

Subunits Comment Organism
More ? * 26000, SDS-PAGE Crotalus atrox

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10.3
-
-
Crotalus atrox

pH Range

pH Minimum pH Maximum Comment Organism
7.5 11
-
Crotalus atrox