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Literature summary for 3.4.23.5 extracted from
- Studies on proteolysis in stored muscle. Part II. Purification and properties of a proteolytic enzyme, cathepsin D, from rabbit muscle (1968), Agric. Biol. Chem., 32, 975-982.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-Cys | - |
Oryctolagus cuniculus |  |
| Mn2+ | 0.01 M, slight decrease in activity | Oryctolagus cuniculus | |
| Monoiodoacetic acid | - |
Oryctolagus cuniculus | |
| Zn2+ | 0.01 M, slight decrease in activity | Oryctolagus cuniculus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | activates | Oryctolagus cuniculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | longissimus dorsi muscle | Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Albumin + H2O | bovine serum albumin | Oryctolagus cuniculus | ? | - |
? | |
| Hemoglobin + H2O | denatured hemoglobin | Oryctolagus cuniculus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | 47 | denatured hemoglobin | Oryctolagus cuniculus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 27 | 52 | 27°C: about 60% of maximal activity, 52°C: about 60% of maximal activity | Oryctolagus cuniculus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
pH 3.0, 10 min, 50% loss of activity | Oryctolagus cuniculus |
| 70 | - |
pH 3.0, 10 min, 90% loss of activity | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4 | - |
denatured hemoglobin | Oryctolagus cuniculus |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 2 | - |
37°C, maximal stability | Oryctolagus cuniculus |
| 3 | - |
10 min, 50% loss of activity at 60°C, 90% loss of activity at 70°C | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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