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Literature summary for 3.4.23.46 extracted from

  • Ellis, C.R.; Shen, J.
    pH-Dependent population shift regulates BACE1 activity and inhibition (2015), J. Am. Chem. Soc., 137, 9543-9546 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.23.46

Inhibitors

Inhibitors Comment Organism Structure
OM99-2
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome
-
 Homo sapiens 5768
-
Golgi apparatus
-
 Homo sapiens 5794
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amyloid-beta precursor protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P56817
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid-beta precursor protein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
BACE1
-
 Homo sapiens
beta-secretase
-
 Homo sapiens
beta-site amyloid precursor protein cleavage enzyme
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
-
 Homo sapiens