Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6,7-furano-5-prenyloxy hydrocoumaric acid | - |
Homo sapiens | |
6,7-furano-5-prenyloxy hydrocoumaric acid methyl ester | - |
Homo sapiens | |
6,7-furano-8a-methoxy-5-prenyloxy hydrocoumaric acid | - |
Homo sapiens | |
6,7-furano-8a-methoxy-5-prenyloxy hydrocoumaric acid methyl ester | competitive-type inhibitor | Homo sapiens | |
imperatorin | - |
Homo sapiens | |
isoimperatorin | - |
Homo sapiens | |
additional information | not inhibited by xanthoxol | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Rh-EVNLDAEFK-quencher + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE1 | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0113 | - |
6,7-furano-8a-methoxy-5-prenyloxy hydrocoumaric acid methyl ester | in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0162 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | 6,7-furano-8a-methoxy-5-prenyloxy hydrocoumaric acid methyl ester | |
0.0305 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | 6,7-furano-5-prenyloxy hydrocoumaric acid methyl ester | |
0.0918 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | imperatorin | |
0.1856 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | 6,7-furano-5-prenyloxy hydrocoumaric acid | |
0.2033 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | 6,7-furano-8a-methoxy-5-prenyloxy hydrocoumaric acid | |
0.2442 | - |
in 50 mM sodium acetate, pH 4.5, at 25°C | Homo sapiens | isoimperatorin |