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Literature summary for 3.4.23.46 extracted from
- Oligemic hypoperfusion differentially affects Tau and amyloid-beta (2010), Am. J. Pathol., 177, 300-310.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| amyloid precursor protein + H2O | Mus musculus | - |
fragments of amyloid precursor protein | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hippocampus | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| amyloid precursor protein + H2O | - |
Mus musculus | fragments of amyloid precursor protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BACE1 | - |
Mus musculus |
| beta-secretase | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | oligemia/mild hypoperfusion produces a long lasting effect on Alzheimers disease related proteins, increasing amyloid-beta levels via enhanced BACE1 expression | up |
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Release 2023.1 (January 2023)
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