Inhibitors | Comment | Organism | Structure |
---|---|---|---|
OM99-2 | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0045 | - |
((7-methoxycoumarin-4-yl)acetyl)-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(2,4-dinitrophenyl) | pro-memapsin 2 | Homo sapiens | |
0.0054 | - |
Arg-Glu(5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(4-(4-dimethylaminophenylazo)benzoic acid)-Arg | pro-memapsin 2 | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50300 | - |
x * 50300, SDS-PAGE, pro-memapsin2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
((7-methoxycoumarin-4-yl)acetyl)-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(2,4-dinitrophenyl) + H2O | i.e. FS-2, cleavage occurs at Leu-Asp bond | Homo sapiens | ((7-methoxycoumarin-4-yl)acetyl)-Ser-Glu-Val-Asn-Leu + Asp-Ala-Glu-Phe-Lys(2,4-dinitrophenyl) | - |
? | |
amyloid precursor protein + H2O | - |
Homo sapiens | ? | - |
? | |
Arg-Glu(5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(4-(4-dimethylaminophenylazo)benzoic acid)-Arg | i.e. FS-1, cleavage occurs at Leu-Asp bond | Homo sapiens | Arg-Glu(5-[(2-aminoethyl)amino]-naphthalene-1-sulfonic acid)-Glu-Val-Asn-Leu + Asp-Ala-Glu-Phe-Lys(4-(4-dimethylaminophenylazo)benzoic acid)-Arg | - |
? | |
Swedish variant of amyloid precursor protein + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50300, SDS-PAGE, pro-memapsin2 | Homo sapiens |
More | stable in vitro activated forms have 44100 and 46100 kDa, depending on activating protease | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000098 | - |
OM99-2 | pro-memapsin 2 | Homo sapiens |