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Literature summary for 3.4.23.41 extracted from

  • Olsen, V.; Cawley, N.X.; Loh, Y.P.
    Yapsin1. Structure, biosynthesis, and specificity (1998), Adv. Exp. Med. Biol., 436, 315-319.
    View publication on PubMed
Search for more literature for 3.4.23.41

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in yeast Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane facing into the periplasmic space Saccharomyces cerevisiae
-
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
hydrolyses various precursor proteins with Arg or Lys in P1, and commonly Arg or Lys also in P2. The P3 amino acid is usually non-polar, but otherwise additional basic amino acids are favourable in both non-prime and prime positions cleavage is enhanced in substrates having additional basic residues flanking the P1 site Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human parathyroid hormone
-
 Saccharomyces cerevisiae ?
-
 ?
pro-alpha-mating factor
-
 Saccharomyces cerevisiae ?
-
 ?
synthetic cholecystokinin
-
 Saccharomyces cerevisiae ?
-
 ?
synthetic proalbumin
-
 Saccharomyces cerevisiae RGVFRR + DEAKSEVAW
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4 4.5
-
 Saccharomyces cerevisiae