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Literature summary for 3.4.23.39 extracted from

  • Liu, J.; Istvan, E.S.; Goldberg, D.E.
    Hemoglobin-degrading plasmepsin II is active as a monomer (2006), J. Biol. Chem., 281, 38682-38688.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
D214A mutation abolishes proteolytic activity Plasmodium sp.
D34A mutation abolishes proteolytic activity Plasmodium sp.
D34S mutation abolishes proteolytic activity Plasmodium sp.
D34S/D214S mutation abolishes proteolytic activity Plasmodium sp.

Organism

Organism UniProt Comment Textmining
Plasmodium sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hemoglobin + H2O
-
Plasmodium sp. ?
-
?

Subunits

Subunits Comment Organism
monomer PM II exists mainly as a monomer in solution and that the monomer is fully functional for catalysis Plasmodium sp.

Synonyms

Synonyms Comment Organism
PM II
-
Plasmodium sp.