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Literature summary for 3.4.23.32 extracted from
- The peptidases from fungi and viruses (2006), Biol. Chem., 387, 1023-1029.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| the three-dimensional structure of SGP is determined by X-ray crystallography. The polypeptide folds into a beta-sandwich that has seven antiparallel beta-strands in each of the two sheets | Scytalidium lignicola |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E136A | mutant loses the ability for self-activation and cleavage of the propeptide. Mutant has no peptidase activity | Scytalidium lignicola |
| Q53A | mutant loses the ability for self-activation and cleavage of the propeptide. Mutant has no peptidase activity | Scytalidium lignicola |
| Q53E | mutant loses the ability for self-activation and cleavage of the propeptide. Mutant has no peptidase activity | Scytalidium lignicola |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ac-FKF-(3S,4S)-phenylstatinyl-LR-NH | - |
Scytalidium lignicola |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000065 | - |
D-2,3-diaminopropionic acid(N-methylanthraniloyl)-GFKFFALRK(2,4-dinitrophenol) | - |
Scytalidium lignicola | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Scytalidium lignicola | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-2,3-diaminopropionic acid(N-methylanthraniloyl)-GFKFFALRK(2,4-dinitrophenol) + H2O | - |
Scytalidium lignicola | D-2,3-diaminopropionic acid(N-methylanthraniloyl)-GFKFF + ALRK(2,4-dinitrophenol) | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| scytalidoglutamic peptidase | - |
Scytalidium lignicola |
| SGP | - |
Scytalidium lignicola |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 34.8 | - |
D-2,3-diaminopropionic acid(N-methylanthraniloyl)-GFKFFALRK(2,4-dinitrophenol) | - |
Scytalidium lignicola | |
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Release 2023.1 (January 2023)
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