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Literature summary for 3.4.23.3 extracted from

  • Auffret, C.A.; Ryle, A.P.
    The catalytic activity of pig pepsin C towards small synthetic substrates (1979), Biochem. J., 179, 239-246.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.23.3

Inhibitors

Inhibitors Comment Organism Structure
Acetyl-Phe hydrolysis of acetyl-Phe-Leu-Val-His-amide Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.28
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-0.15 mM Sus scrofa
0.7
-
 acetyl-Ala-Phe-Leu-Val-His-NH2
-
 Sus scrofa
0.82
-
 acetyl-Tyr-Leu-Val-His-OH
-
 Sus scrofa
0.82
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-0.5 mM Sus scrofa
1.71
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-1.0 mM Sus scrofa
1.84
-
 acetyl-Phe-Leu-Val-His-NH2
-
 Sus scrofa
1.84
-
 acetyl-Phe-Leu-Val-His methyl ester
-
 Sus scrofa
4.31
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-2.0 mM Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-Ala-Leu-Val-His-NH2 + H2O very low activity Sus scrofa ?
-
 ?
acetyl-Ala-Leu-Val-His-OH + H2O very low activity Sus scrofa ?
-
 ?
acetyl-Ala-Phe-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
acetyl-Phe-Leu-Val-His methyl ester + H2O
-
 Sus scrofa ?
-
 ?
acetyl-Phe-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
acetyl-Tyr-Leu-Val-His methyl ester + H2O
-
 Sus scrofa ?
-
 ?
acetyl-Tyr-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
acetyl-Tyr-Leu-Val-His-OH + H2O
-
 Sus scrofa ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.06
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-0.15 mM Sus scrofa
1.07
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-0.5 mM Sus scrofa
1.08
-
 acetyl-Tyr-Leu-Val-His-NH2
-
 Sus scrofa
4.45
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-2.0 mM Sus scrofa
5.13
-
 acetyl-Phe-Leu-Val-His methyl ester
-
 Sus scrofa
5.76
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-1.0 mM Sus scrofa
6.12
-
 acetyl-Phe-Leu-Val-His-NH2
-
 Sus scrofa
7.01
-
 acetyl-Ala-Phe-Leu-Val-His-NH2
-
 Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
-
 Sus scrofa