Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pepstatin | 100 molar excess amount is needed for the complete inhibition of activity of pepsin C-1 and C-2 | Suncus murinus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
pepsinogen C-2, 41000 Da, SDS-PAGE | Suncus murinus |
additional information | - |
pepsinogen C-1, 39000 Da, SDS-PAGE | Suncus murinus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Suncus murinus | - |
pepsin C-1 and C-2 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | pepsinogen C-1 and C-2, each pepsinogen is converted to pepsin through an intermediate form under acidic conditions | Suncus murinus |
side-chain modification | pepsinogen C-2 contains an Asn-linked carbohydrate chain of about 2000 Da | Suncus murinus |
Purification (Comment) | Organism |
---|---|
pepsinogen C-1 and C-2 | Suncus murinus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gastric mucosa | - |
Suncus murinus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Suncus murinus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Hemoglobin + H2O | pepsin C1 and C2 | Suncus murinus | ? | - |
? | |
oxidized insulin B chain + H2O | pepsin C-1 | Suncus murinus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
3 | - |
- |
Suncus murinus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
1.3 | 4.5 | pH 1.3: about 75% of maximal activity, pH 4.5: about 35% of maximal activity, pepsin C-2 | Suncus murinus |
1.4 | 4.5 | pH 1.4: about 90% of maximal activity, pH 4.5: about 40% of maximal activity, pepsin C-1 | Suncus murinus |