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Literature summary for 3.4.23.24 extracted from

  • Yang, H.; Tsang, P.C.S.; Pow, E.H.N.; Lam, O.L.T.; Tsang, P.W.
    Potential role of Candida albicans secreted aspartic protease 9 in serum induced-hyphal formation and interaction with oral epithelial cells (2020), Microb. Pathog., 139, 103896.
    View publication on PubMed
Search for more literature for 3.4.23.24

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Candida albicans
-
-

Organism

Organism UniProt Comment Textmining
Candida albicans Q59SU1
-
-

Synonyms

Synonyms Comment Organism
Sap9
-
 Candida albicans
secreted aspartic protease 9
-
 Candida albicans

General Information

General Information Comment Organism
physiological function SAP9 gene is required for the formation filaments in serum hyphal-inducing conditions. For the SAP deletion mutant, the proportion of cell penetration into oral epithelial cells during infection is significantly smaller compared to the wild type strain. The epithelial cell damage is significantly reduced in SAP9 mutant strains. In addition, the expression level of EFG1 is downregulated by approximately 40% in a SAP9 deletion mutant Candida albicans