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Literature summary for 3.4.23.24 extracted from
- Vaccination with secreted aspartyl proteinase 2 protein from Candida parapsilosis can enhance survival of mice during C. tropicalis-mediated systemic candidiasis (2020), Infect. Immun., 88, e00312.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | vaccination with recombinant Sap2 (rSap2) protein from Candida parapsilosis enhances survival of mice compared to rSap2 vaccinations from Candida albicans, C. tropicalis, and sham immunization. The vaccination induces increased titers of Sap2-specific Ig, IgG, and IgM antibodies, which can bind whole fungus. Sera from Sap2-parapsilosis-vaccinated mice exhibit increased C. tropicalis biofilm inhibition ability in vitro and enhanced neutrophil-mediated fungal killing | Candida parapsilosis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida parapsilosis | A0A7D6WSQ6 | isoform SAP2 | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SAP2 | - |
Candida parapsilosis |
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