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Literature summary for 3.4.23.24 extracted from
- Novel aggregation properties of Candida albicans secreted aspartyl proteinase SAP6 mediate virulence in oral candidiasis (2015), Infect. Immun., 83, 2614-2626 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Pichia pastoris | Candida albicans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | Q5AC08 | - |
- |
| Candida albicans CAI4 | Q5AC08 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE Sephadex A-25 gel filtration and hydroxyapatite column chromatography | Candida albicans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| fluorescein-labeled casein + H2O | - |
Candida albicans | ? | - |
? |  |
| fluorescein-labeled casein + H2O | - |
Candida albicans CAI4 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SAP6 | - |
Candida albicans |
| secreted aspartyl proteinase | - |
Candida albicans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | secreted aspartyl proteinase Sap6 mediates virulence in oral candidiasis. Mice infected sublingually with Candida albicans cells overexpressing Sap6 have thicker fungal plaques and more severe oral infection | Candida albicans |
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