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Literature summary for 3.4.23.24 extracted from
- Isolation and characterization of proteinase from Candida albicans: substrate specificity (1984), J. Invest. Dermatol., 83, 32-36.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,2-epoxy-3-(4-nitrophenoxy)propane | not | Candida albicans |  |
| chymostatin | - |
Candida albicans | |
| Diazoacetylnorleucine methyl ester | not | Candida albicans | |
| pepstatin | - |
Candida albicans | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42000 | - |
Candida albicans, gel filtration | Candida albicans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Candida albicans | the enzyme plays an important role in superficial infection by affecting the human stratum corneum of the skin and nail | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Candida albicans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Albumin + H2O | - |
Candida albicans | ? | - |
? | |
| Hemoglobin + H2O | - |
Candida albicans | ? | - |
? | |
| Human stratum corneum + H2O | - |
Candida albicans | ? | - |
? | |
| Keratin + H2O | - |
Candida albicans | ? | - |
? | |
| additional information | the enzyme plays an important role in superficial infection by affecting the human stratum corneum of the skin and nail | Candida albicans | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 42000, Candida albicans, SDS-PAGE | Candida albicans |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
stable at | Candida albicans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4 | - |
- |
Candida albicans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 2.5 | 6 | inactive below and above | Candida albicans |
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