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Literature summary for 3.4.23.19 extracted from

  • Sasaki, H.; Kojima, M.; Sawano, Y.; Kubota, K.; Suganuma, M.; Muramatsu, T.; Takahashi, K.; Tanokura, M.
    A proposed catalytic mechanism of aspergilloglutamic peptidase from Aspergillus niger (2005), Proc. Jpn. Acad. Ser. B, 81, 441-446.
No PubMed abstract available
Search for more literature for 3.4.23.19

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular the enzyme is secreted Aspergillus niger var. macrosporus
-
-

Organism

Organism UniProt Comment Textmining
Aspergillus niger var. macrosporus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native extracellular enzyme from culture medium Aspergillus niger var. macrosporus

Reaction

Reaction Comment Organism Reaction ID
preferential cleavage in B chain of insulin: Asn3-/-Gln, Gly13-/-Ala, Tyr26-/-Thr catalytic residues are GluB110 and GluB24, detailed catalytic mechanism, overview Aspergillus niger var. macrosporus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin II + H2O
-
 Aspergillus niger var. macrosporus DRVYIH + Pro-Phe
-
 ?
additional information substrate specificity Aspergillus niger var. macrosporus ?
-
 ?
substance P + H2O
-
 Aspergillus niger var. macrosporus RPKPQQFF + Gly-Leu-Met
-
 ?

Synonyms

Synonyms Comment Organism
AGP
-
 Aspergillus niger var. macrosporus
aspergilloglutamic peptidase
-
 Aspergillus niger var. macrosporus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Aspergillus niger var. macrosporus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4 5
-
 Aspergillus niger var. macrosporus

pH Range

pH Minimum pH Maximum Comment Organism
1.5 7 pH profile Aspergillus niger var. macrosporus