Activating Compound | Comment | Organism | Structure |
---|---|---|---|
transglutaminase | incubation of HIV-1 aspartyl protease with transglutaminase increases its catalytic activity in a time- and concentration-dependent manner. Enzyme activity is increased, up to about 170% of control value, after 1 h incubation with 0.008 units of transglutaminase in the presence of Ca2+. The activation is completely abolished by spermidine | Human immunodeficiency virus 1 |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Human immunodeficiency virus 1 |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gag-Pol polyprotein + H2O | Human immunodeficiency virus 1 | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gag-Pol polyprotein + H2O | - |
Human immunodeficiency virus 1 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | - |
Human immunodeficiency virus 1 |
Synonyms | Comment | Organism |
---|---|---|
HIV-1 aspartyl protease | - |
Human immunodeficiency virus 1 |
HIV-1 PR | - |
Human immunodeficiency virus 1 |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is required for virus replication | Human immunodeficiency virus 1 |