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Literature summary for 3.4.23.16 extracted from

  • Lee, J.S.; Miyashiro, H.; Nakamura, N.; Hattori, M.
    Two new triterpenes from the rhizome of Dryopteris crassirhizoma, and inhibitory activities of its constituents on human immunodeficiency virus-1 protease (2008), Chem. Pharm. Bull., 56, 711-714.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-O-acetyldryopteric acid A inhibitor isolated from Dryopteris crassirhizoma Human immunodeficiency virus 1
2-O-acetyldryopteric acid B inhibitor isolated from Dryopteris crassirhizoma Human immunodeficiency virus 1
acetyl-pepstatin
-
Human immunodeficiency virus 1
dryopteric acid A inhibitor isolated from Dryopteris crassirhizoma Human immunodeficiency virus 1
dryopteric acid B inhibitor isolated from Dryopteris crassirhizoma Human immunodeficiency virus 1
ursolic acid
-
Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00009
-
-
Human immunodeficiency virus 1 acetyl-pepstatin
0.0089
-
-
Human immunodeficiency virus 1 ursolic acid
0.0108
-
-
Human immunodeficiency virus 1 2-O-acetyldryopteric acid B
0.017
-
-
Human immunodeficiency virus 1 2-O-acetyldryopteric acid A
0.0265
-
-
Human immunodeficiency virus 1 dryopteric acid A
0.0445
-
-
Human immunodeficiency virus 1 dryopteric acid B