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Literature summary for 3.4.23.16 extracted from
- Specificity of retroviral proteases: an analysis of viral and nonviral protein substrates (1994), Methods Enzymol., 241, 279-301.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| AETFYVDG + H2O | - |
Human immunodeficiency virus 1 | ? | - |
? |  |
| ARVLAEAM + H2O | - |
Human immunodeficiency virus 1 | ARVL + AEAM | - |
? | |
| ATIMMQRG + H2O | - |
Human immunodeficiency virus 1 | ATIM + MQRG | - |
? | |
| additional information | sequences surrounding HIV-1 protease cleavage sites in several viral and nonviral protein substrates. No amino acid is required at any of the eight positions of the substrate. The highest preference is seen for glutamate at P2' followed by Phe at P1 | Human immunodeficiency virus 1 | ? | - |
? | |
| PGNFLESR + H2O | - |
Human immunodeficiency virus 1 | PGNF + LESR | - |
? | |
| RKILFLDG + H2O | - |
Human immunodeficiency virus 1 | RKIL + FLDG | - |
? | |
| SFNFPQIT + H2O | - |
Human immunodeficiency virus 1 | SFNF + PQIT | - |
? | |
| SQNYPIVQ + H2O | - |
Human immunodeficiency virus 1 | SQNY + PIVQ | - |
? | |
| TLNFPISP + H2O | - |
Human immunodeficiency virus 1 | TLNF + PISP | - |
? | |
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