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Literature summary for 3.4.23.15 extracted from

  • Slater, E.E.
    Renin (1981), Methods Enzymol., 80, 427-442.
    View publication on PubMed
Search for more literature for 3.4.23.15

Inhibitors

Inhibitors Comment Organism Structure
1,2-epoxy-3-(p-nitrophenoxy)propane
-
 Mus musculus
Bromoisocaproyl peptides
-
 Homo sapiens
Bromoisocaproyl peptides
-
 Mus musculus
Bromoisocaproyl peptides
-
 Sus scrofa
diazoacetyl methyl ester derivatives of glycine, norleucine, leucine in presence of Cu2+ Mus musculus
pepstatin
-
 Homo sapiens
pepstatin
-
 Mus musculus
pepstatin
-
 Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00154
-
 angiotensinogen human substrate and enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
submandibular gland
-
 Mus musculus
-
submandibular gland
-
 Homo sapiens
-
submandibular gland
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 bioassay Mus musculus
additional information
-
 bioassay Homo sapiens
additional information
-
 bioassay Sus scrofa
additional information
-
 2000 Golblatt units/mg Homo sapiens
additional information
-
 radioimmunoassy Mus musculus
additional information
-
 radioimmunoassy Homo sapiens
additional information
-
 radioimmunoassy Sus scrofa
additional information
-
 fluorimetric assay Mus musculus
additional information
-
 fluorimetric assay Homo sapiens
additional information
-
 fluorimetric assay Sus scrofa

Storage Stability

Storage Stability Organism
-70°C, or -20°C, or 4°C, neutral pH Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Glu + H2O
-
 Mus musculus H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + Val-Ile-His-Thr-Glu
-
 ?
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Glu + H2O
-
 Sus scrofa H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + Val-Ile-His-Thr-Glu
-
 ?