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Literature summary for 3.4.23.15 extracted from

  • Riccioni, G.; Vitulano, N.; D’Orazio, N.; Bellocci, F.
    Aliskiren, the first approved renin inhibitor: Clinical application and safety in the treatment of hypertension (2009), Adv. Ther., 26, 700-710.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
aliskiren low molecular weight, orally active renin inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensinogen + H2O Homo sapiens
-
angiotensin I + angiotensinogen propeptide
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensinogen + H2O
-
Homo sapiens angiotensin I + angiotensinogen propeptide
-
?