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Literature summary for 3.4.23.15 extracted from
- Oral renin inhibitors (2006), Lancet, 368, 1449-1456.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aliskiren | non-peptide orally active renin inhibitor | Homo sapiens |  |
| CGP38560A | - |
Homo sapiens | |
| enalkiren | - |
Homo sapiens | |
| additional information | development of oral renin inhibitors and their pharmacokinetic and pharmacodynamic properties | Homo sapiens | |
| remikiren | - |
Homo sapiens | |
| zankiren | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0000006 | - |
- |
Homo sapiens | aliskiren | |
| 0.0000007 | - |
- |
Homo sapiens | CGP38560A | |
| 0.0000008 | - |
- |
Homo sapiens | remikiren | |
| 0.0000011 | - |
- |
Homo sapiens | zankiren | |
| 0.000014 | - |
- |
Homo sapiens | enalkiren | |
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