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Literature summary for 3.4.23.1 extracted from

  • Li, L.; Yang, D.; Guan, Z.; He, Y.
    Pepsin-catalyzed direct asymmetric aldol reactions for the synthesis of vicinal diol compounds (2015), Tetrahedron, 71, 1659-1667 .
No PubMed abstract available

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric mucosa
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde + 1,3-dihydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4R)-4-(2,2-dimethyl-1,3-dioxolan-4-yl)-1,3,4-trihydroxybutan-2-one
-
?
2,6-dichlorobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(2,6-dichlorophenyl)-3,4-dihydroxybutan-2-one
-
?
2-chlorobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(2-chlorophenyl)-3,4-dihydroxybutan-2-one
-
?
2-nitrobenzaldehyde + 1,3-dihydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-1,3,4-trihydroxy-4-(2-nitrophenyl)butan-2-one
-
?
2-nitrobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-(2-nitrophenyl)butan-2-one
-
?
2-nitrobenzaldehyde + 1-methoxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-hydroxy-3-methoxy-4-(2-nitrophenyl)butan-2-one
-
?
2-nitrobenzaldehyde + cyclohexanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-hydroxy(2-nitrophenyl)methyl]cyclohexan-1-one
-
?
2-nitrobenzaldehyde + cyclopentanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-hydroxy(2-nitrophenyl)methyl]cyclopentan-1-one
-
?
3-bromobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(3-bromophenyl)-3,4-dihydroxybutan-2-one
-
?
3-methylbutanal + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-6-methylheptan-2-one
-
?
3-nitrobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-(3-nitrophenyl)butan-2-one
-
?
3-nitrobenzaldehyde + cyclohexanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-hydroxy(3-nitrophenyl)methyl]cyclohexan-1-one
-
?
4-(trifluoromethyl)benzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-[4-(trifluoromethyl)phenyl]butan-2-one
-
?
4-bromobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(4-bromophenyl)-3,4-dihydroxybutan-2-one
-
?
4-bromobenzaldehyde + propan-2-one in MeCN buffer, at 30°C Sus scrofa (4R)-4-(4-bromophenyl)-4-hydroxybutan-2-one
-
?
4-chlorobenzaldehyde + 1-(benzyloxy)propan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3-(benzyloxy)-4-(4-chlorophenyl)-4-hydroxybutan-2-one
-
?
4-chlorobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(4-chlorophenyl)-3,4-dihydroxybutan-2-one
-
?
4-chlorobenzaldehyde + cyclohexanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-(4-chlorophenyl)(hydroxy)methyl]cyclohexan-1-one
-
?
4-chlorobenzaldehyde + cyclopentanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-(4-chlorophenyl)(hydroxy)methyl]cyclopentan-1-one
-
?
4-fluorobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-(4-fluorophenyl)-3,4-dihydroxybutan-2-one
-
?
4-formylbenzonitrile + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa 4-[(1S,2R)-1,2-dihydroxy-3-oxobutyl]benzonitrile
-
?
4-methylbenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-(4-methylphenyl)butan-2-one
-
?
4-nitrobenzaldehyde + 1,3-dihydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-1,3,4-trihydroxy-4-(4-nitrophenyl)butan-2-one
-
?
4-nitrobenzaldehyde + 1-(benzyloxy)propan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3-(benzyloxy)-4-hydroxy-4-(4-nitrophenyl)butan-2-one
-
?
4-nitrobenzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-(4-nitrophenyl)butan-2-one
-
?
4-nitrobenzaldehyde + 1-methoxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-4-hydroxy-3-methoxy-4-(4-nitrophenyl)butan-2-one
-
?
4-nitrobenzaldehyde + cyclohexanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-hydroxy(4-nitrophenyl)methyl]cyclohexan-1-one
-
?
4-nitrobenzaldehyde + cyclopentanone in MeCN buffer, at 30°C Sus scrofa (2S)-2-[(R)-hydroxy(4-nitrophenyl)methyl]cyclopentan-1-one
-
?
4-nitrobenzaldehyde + oxan-4-one in MeCN buffer, at 30°C Sus scrofa (3S)-3-[(R)-hydroxy(4-nitrophenyl)methyl]oxan-4-one
-
?
4-nitrobenzaldehyde + propan-2-one in MeCN buffer, at 30°C Sus scrofa (4R)-4-hydroxy-4-(4-nitrophenyl)butan-2-one
-
?
4-nitrobenzaldehyde + tert-butyl 4-oxopiperidine-1-carboxylate in MeCN buffer, at 30°C Sus scrofa tert-butyl (3S)-3-[(R)-hydroxy(4-nitrophenyl)methyl]-4-oxopiperidine-1-carboxylate
-
?
4-nitrobenzaldehyde + thian-4-one in MeCN buffer, at 30°C Sus scrofa (3S)-3-[(R)-hydroxy(4-nitrophenyl)methyl]thian-4-one
-
?
benzaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-phenylbutan-2-one
-
?
naphthalene-1-carbaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4S)-3,4-dihydroxy-4-(naphthalen-1-yl)butan-2-one
-
?
thiophene-2-carbaldehyde + 1-hydroxypropan-2-one in MeCN buffer, at 30°C Sus scrofa (3R,4R)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one
-
?

Synonyms

Synonyms Comment Organism
pepsin
-
Sus scrofa