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Literature summary for 3.4.23.1 extracted from
- Studies on the specificity of pepsin (1967), Biochemistry, 6, 1765-1777.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | - |
Sus scrofa |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.18 | - |
benzyloxycarbonyl-His-Phe-Phe-O-ethyl ester | - |
Sus scrofa |  |
| 0.25 | - |
benzyloxycarbonyl-His-Trp-Phe-O-methyl ester | - |
Sus scrofa | |
| 0.37 | - |
benzyloxycarbonyl-His-Phe-Phe-O-methyl ester | - |
Sus scrofa | |
| 0.49 | - |
benzyloxycarbonyl-His-Phe-Phe-NH2 | - |
Sus scrofa | |
| 0.68 | - |
benzyloxycarbonyl-His-Tyr-Phe-O-methyl ester | - |
Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-His-Phe(NO2)-beta-phenyl-L-lactyl-O-methyl ester + H2O | - |
Sus scrofa | benzyloxycarbonyl-His-Phe(NO2) + phenyl-L-lactyl-O-methyl ester | - |
? | |
| benzyloxycarbonyl-His-Phe-Phe-NH2 + H2O | - |
Sus scrofa | ? | - |
? | |
| benzyloxycarbonyl-His-Phe-Phe-O-ethyl ester + H2O | - |
Sus scrofa | ? | - |
? | |
| benzyloxycarbonyl-His-Phe-Phe-O-methyl ester + H2O | - |
Sus scrofa | ? | - |
? | |
| benzyloxycarbonyl-His-Trp-Phe-O-methyl ester + H2O | - |
Sus scrofa | ? | - |
? | |
| benzyloxycarbonyl-His-Tyr-Phe-O-methyl ester + H2O | - |
Sus scrofa | ? | - |
? | |
| additional information | preference for hydrophobic L-amino acid residues on both sides of X-Y bond in benzyloxycarbonyl-L-histidyl-X-Y-OR | Sus scrofa | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.013 | - |
benzyloxycarbonyl-His-Trp-Phe-O-methyl ester | - |
Sus scrofa | |
| 0.013 | - |
benzyloxycarbonyl-His-Tyr-Phe-O-methyl ester | - |
Sus scrofa | |
| 0.15 | - |
benzyloxycarbonyl-His-Phe-Phe-O-methyl ester | - |
Sus scrofa | |
| 0.21 | - |
benzyloxycarbonyl-His-Phe-Phe-NH2 | - |
Sus scrofa | |
| 0.31 | - |
benzyloxycarbonyl-His-Phe-Phe-O-ethyl ester | - |
Sus scrofa | |
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