Inhibitors | Comment | Organism | Structure |
---|---|---|---|
celastrol | competitive inhibitor | Severe acute respiratory syndrome-related coronavirus | |
curcumin | - |
Severe acute respiratory syndrome-related coronavirus | |
dihydrocelastrol | - |
Severe acute respiratory syndrome-related coronavirus | |
iguesterin | competitive inhibitor | Severe acute respiratory syndrome-related coronavirus | |
pristimerin | competitive inhibitor | Severe acute respiratory syndrome-related coronavirus | |
tingenone | competitive inhibitor | Severe acute respiratory syndrome-related coronavirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome-related coronavirus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
commercial preparation | Severe acute respiratory syndrome-related coronavirus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DABCYL-Lys-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys-Glu-EDANS + H2O | - |
Severe acute respiratory syndrome-related coronavirus | DABCYL-Lys-Asn-Ser-Thr-Leu-Gln + Ser-Gly-Leu-Arg-Lys-Glu-EDANS | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SARS-CoV 3CLpro | - |
Severe acute respiratory syndrome-related coronavirus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0008 | - |
iguesterin | - |
Severe acute respiratory syndrome-related coronavirus | |
0.0031 | - |
pristimerin | - |
Severe acute respiratory syndrome-related coronavirus | |
0.004 | - |
tingenone | - |
Severe acute respiratory syndrome-related coronavirus | |
0.0042 | - |
celastrol | - |
Severe acute respiratory syndrome-related coronavirus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0026 | - |
- |
Severe acute respiratory syndrome-related coronavirus | iguesterin | |
0.0055 | - |
- |
Severe acute respiratory syndrome-related coronavirus | pristimerin | |
0.0099 | - |
- |
Severe acute respiratory syndrome-related coronavirus | tingenone | |
0.0103 | - |
- |
Severe acute respiratory syndrome-related coronavirus | celastrol | |
0.0217 | - |
- |
Severe acute respiratory syndrome-related coronavirus | dihydrocelastrol | |
0.0235 | - |
- |
Severe acute respiratory syndrome-related coronavirus | curcumin |