Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cysteine | the enzyme is completely dependent on preactivation with cysteine | Dermatophagoides pteronyssinus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
E-64 | - |
Dermatophagoides pteronyssinus | |
iodoacetamide | - |
Dermatophagoides pteronyssinus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Dermatophagoides pteronyssinus | Der p 1 is the most immunodominant allergen involved in the expression of dust mite-specific immunoglobulin (Ig)E-mediated hypersensitivity. The proteolytic activity of Der p 1 is a major contributor to its allergenicity. Cysteine protease activity of Der p 1 enhances total IgE production | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dermatophagoides pteronyssinus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
feces | - |
Dermatophagoides pteronyssinus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CD25 + H2O | - |
Dermatophagoides pteronyssinus | ? | - |
? | |
additional information | Der p 1 is the most immunodominant allergen involved in the expression of dust mite-specific immunoglobulin (Ig)E-mediated hypersensitivity. The proteolytic activity of Der p 1 is a major contributor to its allergenicity. Cysteine protease activity of Der p 1 enhances total IgE production | Dermatophagoides pteronyssinus | ? | - |
? |