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Literature summary for 3.4.22.63 extracted from

  • Krug, H.F.
    Caspase-10 is the key initiator caspase involved in tributyltin-mediated apoptosis in human immune cells (2012), J. Toxicol., 2012, 395482.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
Homo sapiens
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T-lymphocyte
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Homo sapiens
-

General Information

General Information Comment Organism
malfunction apoptosis is totally prevented when caspase-10 is specifically inhibited in the cells Homo sapiens
physiological function caspase-10 is the key initiator caspase involved in tributyltin-mediated apoptosis in immune cells. Caspase-10 is recruited by the TRAIL-R2 receptor Homo sapiens