Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DEVD-aldehyde | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.13 | - |
DEVD-7-amido-4-methylcoumarin | pH 7.5 | Homo sapiens | |
0.15 | - |
YVAD-7-amido-4-methylcoumarin | pH 7.5 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q92851 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | Mch4 is derived from a single chain proenzym, granzyme B cleaves proMch4 at a IXXD-A processing sequence to produce mature Mch4 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
JURKAT cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CPP32 + H2O | - |
Homo sapiens | ? | - |
? | |
DEVD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | DEVD + 7-amino-4-methylcoumarin | - |
? | |
pro-Mch3 + H2O | cleaves the propeptide of Mch3 to generate a 33000 Da protein which is further processed to the 20000 Da band and the 12000 Da protein | Homo sapiens | ? | - |
? | |
YVAD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | YVAD + 7-amino-4-methylcoumarin | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000014 | - |
DEVD-aldehyde | pH 7.5 | Homo sapiens |