Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.62 extracted from

  • Coen, L.; Le Blay, K.; Rowe, I.; Demeneix, B.A.
    Caspase-9 regulates apoptosis/proliferation balance during metamorphic brain remodeling in Xenopus (2007), Proc. Natl. Acad. Sci. USA, 104, 8502-8507.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Xenopus laevis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain caspase-9 is highly expressed in tadpole brain during metamorphosis. Caspase-9 mRNA is expressed mainly in the ventricular area, a site of neuroblast proliferation. Caspase-9, a key members of the mitochondrial death pathway, is implicated in controlling the proliferative status of neuroblasts in the metamorphosing Xenopus brain. Modification of the expression during the critical period of metamorphosis alters the outcome of metamorphic neurogenesis, resulting in a modified brain phenotype in juvenile Xenopus Xenopus laevis
-