Literature summary for 3.4.22.62 extracted from

Allan, L.A.; Clarke, P.R.
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis (2007), Mol. Cell, 26, 301-310.

Search for more literature for 3.4.22.62

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	caspase-9 is regulated during cell cycle through periodic phosphorylation at an inhibitory site, Thr125. This site is phosphorylated by CDK1/cyclin B1 during mitosis and in response to microtubule poisons that arrest cells at this stage of the cell cyclce. Phosphorylation of caspase-9 at Thr125 protects mitoctic cells against apoptosis	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-

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Release 2023.1 (January 2023)