Literature summary for 3.4.22.62 extracted from

Samraj, A.K.; Keil, E.; Ueffing, N.; Schulze-Osthoff, K.; Schmitz, I.
Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis (2006), J. Biol. Chem., 281, 29652-29659.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
JURKAT cell	caspase-9-deficient cells reveal strongly impaired apoptosis, caspase activation, and mitochondrial membrane depolarization upon CD95 triggering. Caspase-9-deficient Jurkat line JMR will prove a very useful tool for further analysis of cell death mechanisms in the absence of apoptosome function	Homo sapiens	-

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Release 2023.1 (January 2023)