Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | caspase-9 plays a crucial role in the initiation of the initiation phase of the intrinsic apoptosis pathway. Caspase-9 gene mutation may not contribute to the pathogenesis of human cancer (gastric, colorectal and lung carcinomas) | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colonic adenocarcinoma cell | caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer | Homo sapiens | - |
colorectal adenocarcinoma cell | from cecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum. Caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer | Homo sapiens | - |
gastric cancer cell | caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer | Homo sapiens | - |
gastric carcinoma cell | caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer | Homo sapiens | - |
lung adenocarcinoma cell | caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | caspase-9 plays a crucial role in the initiation of the initiation phase of the intrinsic apoptosis pathway. Caspase-9 gene mutation may not contribute to the pathogenesis of human cancer (gastric, colorectal and lung carcinomas) | Homo sapiens | ? | - |
? |