Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.61 extracted from

  • Danelishvili, L.; Yamazaki, Y.; Selker, J.; Bermudez, L.E.
    Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis (2010), PLoS ONE, 5, e10474.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
Homo sapiens
-
U-937 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
FLICE
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens inactivation of protein-associated splicing factor by siRNA significantly decreases the level of caspase-8 in macrophages, significant suppression of caspase-8 activation is observed in both macrophages infected with wild type Mycobacterium tuberculosis H37Rv and with the complemented 31G12 strain containing the pLD31G12-3 construct down
Homo sapiens recombinant tumor necrosis actor-alpha-treated and Mycobacterium tuberculosis 31G12-infected macrophages show caspase-8 activation up