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Literature summary for 3.4.22.61 extracted from

  • Bai, J.; Meng, Z.
    Expression of caspase and apoptotic signal pathway induced by sulfur dioxide (2010), Environ. Mol. Mutagen., 51, 112-122.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9JHX4 isoform CRA_a
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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Rattus norvegicus
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lung
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
IETD-4-nitroanilide + H2O
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Rattus norvegicus IETD + 4-nitroaniline
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?

Synonyms

Synonyms Comment Organism
caspase 8
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Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus mRNA levels, protein levels and activity of caspase-8 is increased in a dose-dependent manner in livers (up to 2.14fold) and lungs (up to 2.12fold) of rats after SO2 inhalation (treated with 14, 28, and 56 mg/m3 SO2 for 7 days at 6 h/day) up