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Literature summary for 3.4.22.61 extracted from
- Mechanism of activation of dsRNA-dependent protein kinase (PKR) in muscle atrophy (2010), Cell. Signal., 22, 783-790.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| IETD-CHO | specific caspase-8 inhibitor | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| C2C12 cell | - |
Mus musculus | - |
| myotube | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-IETD-7-amido-4-trifluoromethylcoumarin + H2O | - |
Mus musculus | benzyloxycarbonyl-IETD + 7-amino-4-trifluoromethylcoumarin | - |
? | |
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Release 2023.1 (January 2023)
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