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Literature summary for 3.4.22.61 extracted from

  • Kamimatsuse, A.; Matsuura, K.; Moriya, S.; Fukuba, I.; Yamaoka, H.; Fukuda, E.; Kamei, N.; Hiyama, K.; Sueda, T.; Hiyama, E.
    Detection of CpG island hypermethylation of caspase-8 in neuroblastoma using an oligonucleotide array (2009), Pediatr. Blood Cancer, 52, 777-783.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene CASP8, located at chromosome 2q33-q34, DNA and amino acid sequence determination and analysis, quantitative expression analysis in neuroblastoma cells by RT-PCR, determination of methylation status of a CpG island located between exons 2 and 3 of caspase 8 in neuroblastomas, methylation inactivates the geneoverview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens caspase 8 is an initiator caspase that plays an important role in the Fas-Fas ligand pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
gene CASP8
-

Source Tissue

Source Tissue Comment Organism Textmining
neuroblastoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information caspase 8 is an initiator caspase that plays an important role in the Fas-Fas ligand pathway Homo sapiens ?
-
?