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Literature summary for 3.4.22.61 extracted from

  • French, C.J.; Spees, J.L.; Zaman, A.K.; Taatjes, D.J.; Sobel, B.E.
    The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion (2009), FASEB J., 23, 1177-1185.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.61

Activating Compound

Activating Compound Comment Organism Structure
additional information dexamethasone induces the enzyme in thymus Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus apoptosis in ischemic hearts occurs through the receptor-mediated extrinsic caspase-8 apoptotic pathway as opposed to the mitochondrial caspase-3 pathway, overview ?
-
 ?
additional information Mus musculus C57BL6 apoptosis in ischemic hearts occurs through the receptor-mediated extrinsic caspase-8 apoptotic pathway as opposed to the mitochondrial caspase-3 pathway, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 C57Bl6 mice
-
Mus musculus C57BL6
-
 C57Bl6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
heart caspase-8 activity is similar in healthy and myocardial ischemic hearts Mus musculus
-
thymus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information apoptosis in ischemic hearts occurs through the receptor-mediated extrinsic caspase-8 apoptotic pathway as opposed to the mitochondrial caspase-3 pathway, overview Mus musculus ?
-
 ?
additional information apoptosis in ischemic hearts occurs through the receptor-mediated extrinsic caspase-8 apoptotic pathway as opposed to the mitochondrial caspase-3 pathway, overview Mus musculus C57BL6 ?
-
 ?

Synonyms

Synonyms Comment Organism
caspase 8
-
 Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus