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Literature summary for 3.4.22.61 extracted from
- Caspase-8 Regulation by Direct Interaction with TRAF6 in T Cell Receptor-Induced NF-kappaB Activation (2006), Curr. Biol., 16, 1666-1671.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in HEK293T cells | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E396A | diminishes TRAF6 binding capacity | Homo sapiens |
| E417A | diminishes TRAF6 binding capacity | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| biotin-conjugated valine-alanine-aspartate-fluoromethylketone | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lipid raft | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q14790 | ? | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| JURKAT cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| caspase-8 | - |
Homo sapiens |
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