Literature summary for 3.4.22.61 extracted from

Juo, P.; Kuo, C.J.; Yuan, J.; Blenis, J.
Essential requiremnt for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade (1998), Curr. Biol., 8, 1001-1008.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	caspase-8 occupies an essential and apical position in the fas signaling pathway and suggests that caspase-8 may participate broadly in multiple apoptotic pathways	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	caspase-8 occupies an essential and apical position in the fas signaling pathway and suggests that caspase-8 may participate broadly in multiple apoptotic pathways	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)