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Literature summary for 3.4.22.60 extracted from
- Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis (2013), BMC Cell Biol., 14, 32.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Boc-Asp-fluoromethylketone | - |
Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MEF cell | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Casp7 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | caspase-7-deficient MEF cells are not resistance to intrinsic cell death, but remain attached to the extracellular matrix | Mus musculus |
| physiological function | caspase-7 is required for apoptotic cell detachment and contributes to reactive oxygen species production | Mus musculus |
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Release 2023.1 (January 2023)
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