Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.60 extracted from

  • Walsh, J.G.; Cullen, S.P.; Sheridan, C.; Luethi, A.U.; Gerner, C.; Martin, S.J.
    Executioner caspase-3 and caspase-7 are functionally distinct proteases (2008), Proc. Natl. Acad. Sci. USA, 105, 12815-12819.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.60

Cloned(Commentary)

Cloned (Comment) Organism
gene CASP-7, expression in Escherichia coli strain BL21(DE3) Mus musculus
gene CASP-7, expression in Escherichia coli strain BL21(DE3) Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information comparison of phenotypes of caspase-7 with caspase-3 deficient cells, overview Mus musculus
additional information comparison of phenotypes of caspase-7 with caspase-3 deficient cells, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis, the major executioner caspases are caspase-3 and caspase-7, which show overlapping substrate specificities, overview ?
-
 ?
additional information Homo sapiens members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis, the major executioner caspases are caspase-3 and caspase-7, which show overlapping substrate specificities, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 gene CASP-7
-
Mus musculus
-
 gene CASP-7
-

Source Tissue

Source Tissue Comment Organism Textmining
J-774 cell
-
 Mus musculus
-
JURKAT cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis, the major executioner caspases are caspase-3 and caspase-7, which show overlapping substrate specificities, overview Mus musculus ?
-
 ?
additional information members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis, the major executioner caspases are caspase-3 and caspase-7, which show overlapping substrate specificities, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
More caspase-7 is a member of the caspase family of cysteine proteases Homo sapiens
More caspase-7 is a members of the caspase family of cysteine proteases Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus
7.4
-
 assay at Homo sapiens