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Literature summary for 3.4.22.60 extracted from

  • Machleidt, T.; Geller, P.; Schwandner, R.; Scherer, G.; Kronke, M.
    Caspase 7-induced cleavage of kinectin in apoptotic cells (1998), FEBS Lett., 436, 51-54.
    View publication on PubMed
Search for more literature for 3.4.22.60

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
kinectin + H2O Homo sapiens kinectin is cleaved by caspase 7 during apoptosis induced by different stimuli. Kinectin functions as a membrane anchor for kinesin and may be relevant to the disruption of vesicle trafficking during apoptosis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-
JURKAT cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
kinectin + H2O proteolytic cleavage of the 160000 Da enzyme form to a 120000 Da fragment Homo sapiens ?
-
 ?
kinectin + H2O kinectin is cleaved by caspase 7 during apoptosis induced by different stimuli. Kinectin functions as a membrane anchor for kinesin and may be relevant to the disruption of vesicle trafficking during apoptosis Homo sapiens ?
-
 ?