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Literature summary for 3.4.22.56 extracted from

  • Aghazadeh, S.; Amini, R.; Yazdanparast, R.; Ghaffari, S.H.
    Anti-apoptotic and anti-inflammatory effects of Silybum marianum in treatment of experimental steatohepatitis (2011), Exp. Toxicol. Pathol., 63, 569-574.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Bid peptide + H2O Rattus norvegicus
-
 ?
-
 ?
procaspase-3 + H2O Rattus norvegicus
-
 caspase-3 + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Bid peptide + H2O
-
 Rattus norvegicus ?
-
 ?
IETD-4-nitroanilide + H2O
-
 Rattus norvegicus IETD + 4-nitroaniline
-
 ?
procaspase-3 + H2O
-
 Rattus norvegicus caspase-3 + ?
-
 ?

Expression

Organism Comment Expression
Rattus norvegicus crude Silybum marianum extract treatments significantly lower activation of procaspase-3 to active caspase-3 down