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Literature summary for 3.4.22.56 extracted from

  • Yabu, T.; Kishi, S.; Okazaki, T.; Yamashita, M.
    Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo (2001), Biochem. J., 360, 39-47.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio
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-
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Source Tissue

Source Tissue Comment Organism Textmining
embryo present in early embryos up to the 1000-cell stage as a maternal factor, and is then expressed throughout the body after the gastrula stage by zygotic expression Danio rerio
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-DEVD-7-amido-4-methylcoumarin + H2O high activity Danio rerio acetyl-DEVD + 7-amino-4-methylcoumarin
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?
acetyl-IETD-7-amido-4-methylcoumarin + H2O low activity towards the caspase-6 and caspase-8 substrate Danio rerio acetyl-IETD + 7-amino-4-methylcoumarin
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?
acetyl-LEHD-7-amido-4-methylcoumarin + H2O low activity towards the caspase-9 substrate Danio rerio acetyl-LEHD + 7-amino-4-methylcoumarin
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?
acetyl-YVAD-7-amido-4-methylcoumarin + H2O low activity towards the caspase-1 substrate Danio rerio acetyl-YVAD + 7-amino-4-methylcoumarin
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?