Literature summary for 3.4.22.56 extracted from

Shin, S.; Sung, B.J.; Cho, Y.S.; Kim, H.J.; Ha, N.C.; Hwang, J.I.; Chung, C.W.; Jung, Y.K.; Oh, B.H.
An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7 (2001), Biochemistry, 40, 1117-1123.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
survivin	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-DEVD-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	acetyl-DEVD + 7-amino-4-methylcoumarin	-	?
poly(ADP-ribose) polymerase + H2O	-	Homo sapiens	?	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000036	-	survivin	pH 7.5, 37°C	Homo sapiens

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Release 2023.1 (January 2023)