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Literature summary for 3.4.22.56 extracted from

  • Hirata, H.; Takahashi, A.; Kobayashi, S.; Yonehara, S.; Sawai, H.; Okazaki, T.; Yamamoto, K.; Sasada, M.
    Caspases are activated in a branched protease cascade and control didtinct downstream processes in fas-induced apoptosis (1998), J. Exp. Med., 187, 587-600.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.56

Inhibitors

Inhibitors Comment Organism Structure
acetyl-Asp-Met-Gln-Asp-aldehyde
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nuclear mitotic apparatus protein + H2O Homo sapiens
-
 ?
-
 ?
PAK2 + H2O Homo sapiens caspase-3 is mainly responsible for the apoptotic cleavage of PAK2 in Fas-stimulated Jurkat cells ?
-
 ?
pro-caspase-6 + H2O Homo sapiens caspase-8 activates caspase-3, and caspase-3 in turn activates caspase-6. Caspase 3 has a major role in nuclear apoptosis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell Fas stimulated Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nuclear mitotic apparatus protein + H2O
-
 Homo sapiens ?
-
 ?
nuclear mitotic apparatus protein + H2O cleavage at sites distinct from caspase-6 Homo sapiens ?
-
 ?
PAK2 + H2O caspase-3 is mainly responsible for the apoptotic cleavage of PAK2 in Fas-stimulated Jurkat cells Homo sapiens ?
-
 ?
pro-caspase-6 + H2O caspase-8 activates caspase-3, and caspase-3 in turn activates caspase-6. Caspase 3 has a major role in nuclear apoptosis Homo sapiens ?
-
 ?